In this study, 2632 physical examination population were divided into healthy controls, sub-health fatigue group, and disease fatigue group. Complex network technology was used to screen out core symptoms and Western medicine indexes of sub-health fatigue and disease fatigue population. Pajek software was used to construct core symptom/index network and core symptom-index combined network. #Canonical correlatio spss version 25 software Simultaneously, canonical correlation analysis was used to analyze the objective tongue and pulse data between the two groups of fatigue population and analyze the distribution of tongue and pulse data. Some similarities were found in the core symptoms of sub-health fatigue and disease fatigue population, but with different node importance. The node-importance difference indicated that the diagnostic contribution rate of the same symptom to the two groups was different. The canonical correlation coefficient of tongue and pulse data in the disease fatigue group was 0.42 ( P < 0.05), on the contrast, correlation analysis of tongue and pulse in the sub-health fatigue group showed no statistical significance. The complex network technology was suitable for correlation analysis of symptoms and indexes in fatigue population, and tongue and pulse data had a certain diagnostic contribution to the classification of fatigue population.įatigue is a state in which the body cannot initiate or maintain a certain intensity of activity, or manifest a pathological dysfunction during the initiation or maintenance of voluntary activity. It is a physiological manifestation of body's self-regulation, and a pathological result of certain diseases. Fatigue is a non-specific symptom with certain heritability. It is ubiquitous in sub-health and various diseases, such as Parkinson’s, major depressive disorder, schizophrenia, and cancer. It has become one of the main factors harmful to human's physical and mental health with a serious decline in work efficiency and life quality.

Sub-health status is defined as the decline in vitality, physiological function, and adaptation capacity, but in general not meeting the diagnostic criteria for clinical or sub-clinical diseases. It has attracted extensive attention with the increasing incidence of sub-health in recent years.

Sub-health state of fatigue is one of the most common sub-health types with that fatigue as the chief complaint. The etiology and pathogenesis of fatigue are largely unknown.

#Canonical correlatio spss version 25 software.

Canonical correlation spss version 25